Searchable abstracts of presentations at key conferences in endocrinology

ea0007p98 | Endocrine tumours and neoplasia | BES2004

Diagnosis - 'query acromegaly'

Hordern S , Banu G , Nussey S

A 71 year old obese lady was noticed to have acromegalic facies and bilateral carpal tunnel syndrome, increasing ring and shoe size, but no sweats or headaches. Random IGF-1 was raised (39.1nanomol per litre). Following oral glucose tolerance test (OGTT) fasting glucose was normal but impaired at 2hours (4.8 and 9.6millimol per litre respectively), growth hormone (GH) suppressed from a baseline of 3.8microunits per litre to 2.2microunits per litre. Following thyrotropin releas...

ea0029p1751 | Thyroid cancer | ICEECE2012

Androgen receptor expression in human thyroid cancer tissues: a potential mechanism underlying the gender bias in the incidence of thyroid cancers

Stanley J , Esakky S , Ramalingam N , Kannan A , Maharajan C , Aruldhas M , Banu S

Gender bias in the incidence of thyroid cancer is well known, however, the underlying mechanism is largely unknown. The current study determines variations in the molecular characteristics of thyroid cancers between men and women. Normal and cancerous thyroid tissues were collected from a total of 125 men and women who underwent surgical removal of the thyroid gland. Elevated levels of testosterone in serum and thyroid cancer tissues were observed in women while it decreased i...